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Direct interaction between ABCA1 and HIV-1 Nef: Molecular modeling and virtual screening for inhibitors

Site-specific protein ubiquitylation using an engineered, chimeric E1 activating enzyme and E2 SUMO conjugating enzyme Ubc9

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Some of them are now in Phase I and Phase II clinical trials

Vielhaber S, Kunz D, Winkler K et al (2000) Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis